Process for the preparation of drospirenone
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United States of America Patent
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Jan 13, 2015
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app pub date -
Jul 19, 2012
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Jul 25, 2011
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Abstract
A process is described, comprising the oxidation of 17α-(3-hydroxypropyl)-6β,7β,15β,16β-dimethylen-5β-androstan-3β,5,17β-triol, for the preparation of drospirenone, a synthetic steroid with progestogenic, antimineralocorticoid and antiandrogenic activity, useful for preparing pharmaceutical compositions with contraceptive action.
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