Process for obtaining dronedarone
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United States of America Patent
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Jan 6, 2015
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N/A
app pub date -
Oct 18, 2011
filing date -
Oct 21, 2010
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Abstract
The present invention provides a process for obtaining dronedarone or salts thereof characterized in that in an organic phase comprising one or more non-polar solvents, 5-amino-3-[4-(3-di-n-butylaminopropoxy)benzoyl]-2-n-butyl-benzofuran is reacted with methane sulfonyl chloride without the addition of a base. The invention also provides a process for obtaining intermediates of dronedarone environmentally friendly and industrially viable.
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