Promoter for regeneration of tendon-bone junction tissue or ligament-bone junction tissue
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United States of America Patent
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Jan 6, 2015
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Oct 8, 2009
filing date -
Oct 10, 2008
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Abstract
An object of the present invention is to provide a drug for promoting the regeneration of tendon-bone junction tissue or ligament-bone junction tissue. The present invention relates to a promoter for regeneration of tendon-bone junction tissue or ligament-bone junction tissue including the following (1) or (2) as an active ingredient:
- (1) the following (1-a), (1-b), or (1-c) (1-a) HGF protein,(1-b) a partial peptide of HGF protein, the peptide having an effect of promoting regeneration of tendon-bone junction tissue or ligament-bone junction tissue,(1-c) a salt of (1-a) or (1-b); (2) DNA including the following (2-a), (2-b), or (2-c), (2-a) DNA encoding HGF protein,(2-b) DNA encoding a partial peptide of HGF protein, the peptide having an effect of promoting regeneration of tendon-bone junction tissue or ligament-bone junction tissue,(2-c) DNA encoding a protein or a peptide, the protein or the peptide having an effect of promoting regeneration of tendon-bone junction tissue or ligament-bone junction tissue, and the DNA hybridizing with DNA comprising a base sequence complementary to (2-a) or (2-b) under a stringent condition.
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