Biocompatible, non-biodegradable, non-toxic polymer useful for nanoparticle pharmaceutical compositions

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United States of America Patent

PATENT NO 8927023
SERIAL NO

13633638

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Abstract

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The invention relates to a biocompatible, non-biodegradable, and non-toxic polymer of formula (I), comprising of three monomeric units, selected from 1-Vinylpyrrolidne (VP), N-Isopropylactylamide (NIPAM), and ester of Maleic anhydride and Polyethylene glycol (MPEG), cross-linked with a bi-functional vinyl derivative, of high purity and substantially free of respective toxic monomeric contaminants, and a process for preparation thereof. The invention further relates to nanoparticulate pharmaceutical compositions of poorly water-soluble drugs or compounds comprising the polymer of the invention, which are safe, less-toxic and convenient for bedside administration to patients in need thereof. Furthermore, the invention relates to a highly selective method for preparation of nanoparticulate pharmaceutical compositions of poorly water-soluble drugs or compounds.

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Patent Owner(s)

Patent OwnerAddress
FRESENIUS KABI ONCOLOGY LIMITEDNEW DELHI 110 066

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burman, Anand C Ghaziabad, IN 32 284
Gupta, Pawan Kumar Ghaziabad, IN 10 124
Jaggi, Manu Ghaziabad, IN 40 221
Khattar, Dhiraj Ghaziabad, IN 26 202
Kumar, Mukesh Ghaziabad, IN 350 2983
Mukherjee, Rama Ghaziabad, IN 41 322
Mullick, Sanjoy Ghaziabad, IN 23 328
Praveen, Rajendran Ghaziabad, IN 4 63
Prusthy, Deepak Ghaziabad, IN 2 54
Singh, Manoj Kumar Ghaziabad, IN 83 700
Singh, Shobhit Ghaziabad, IN 3 54

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