Modified ubiquitin proteins having a specific binding activity for the extradomain B of fibronectin
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United States of America Patent
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Dec 30, 2014
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app pub date -
Dec 14, 2010
filing date -
Dec 14, 2009
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Abstract
The present invention refers to novel hetero-multimeric proteins obtained from modified ubiquitin capable of binding the extradomain B of fibronectin (ED-B) with high affinity. Furthermore, the invention refers to fusion proteins comprising said recombinant protein fused to a pharmaceutically and/or diagnostically active component. The invention is further directed to the use of said proteins in medical treatment methods.
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