Compositions and methods for dehydrated storage of on-board reagents in microfluidic devices
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United States of America Patent
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Dec 30, 2014
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Dec 12, 2011
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Jun 12, 2009
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Abstract
Manufacturing methods and compositions are described for production of self-contained microfluidic cartridge devices with on-board reagents for molecular biological testing. Sensitive reagents are stored in dry form without lyophilization or freezing, and reconstituted at the point of use with either a biological sample or a sample eluate at the point of use. Manufacturing methods include sheet and roll fabrication processes where the reagents are printed in place and sealed within individual microfluidic cartridges before gel vitrification.
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