Acid addition salt of a nortriptyline-GABA conjugate and a process of preparing same
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United States of America Patent
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Dec 23, 2014
Grant Date -
Jul 18, 2013
app pub date -
Sep 22, 2011
filing date -
Sep 22, 2010
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Abstract
An acid addition salt of a nortriptyline-GABA conjugate, a novel crystalline form of a fumaric acid addition salt of a nortriptyline-GABA conjugate, and processes of preparing the forgoing are disclosed. Uses of the above-indicated forms of a nortriptyline-GABA conjugate in the treatment of CNS disorders, and in the treatment of pain in particular, are also disclosed. Further disclosed in a large-scale process of preparing a nortriptyline-GABA conjugate.
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