4-(substituted anilino)-quinazoline derivatives useful as tyrosine kinase inhibitors
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United States of America Patent
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Dec 23, 2014
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Sep 20, 2010
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Sep 28, 2009
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Abstract
The present invention relates to 4-(substituted anilino)-quinazoline derivatives as tyrosine kinase inhibitors. Specifically, compounds of formula I, or pharmaceutically acceptable salts or solvates thereof are disclosed, in which each substitutent in formula I is defined in the description. Preparation method of the compounds of formula I, pharmaceutical compositions and pharmaceutical uses thereof are also disclosed. The compounds of formula I are effective tyrosine kinase inhibitors.
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