s. typhimurium, its use and a method to obtain a therapeutic vaccine vector
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United States of America Patent
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Dec 23, 2014
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Feb 23, 2010
filing date -
Feb 23, 2009
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Abstract
The present invention relates to a new bacterial strain of Samonella enterica serovar Typhimurium VNP20009 deposited in the Polish Collection of Microorganisms under access no. B/00024 and its us in the production of a vaccine, especially an anti-cancer vaccine. The present invention also relates to a method of obtaining a therapeutic vaccine vector, characterized in that a genetic modification is introduced into the vector strain specific to cancer cells, resulting in the delayed over expression of a gene encoding a protein responsible for the invasive ability of this strain.
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