Methods of enhancing adjuvaticity of vaccine compositions
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United States of America Patent
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Dec 23, 2014
Grant Date -
Nov 11, 2010
app pub date -
Aug 28, 2008
filing date -
Aug 29, 2007
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Abstract
The immunogenicity of vaccines is enhanced by co-administering a synthetic glycolipid, designated PBS-57, with the vaccine. PBS-57 has the ability to stimulate both a cell-mediated and humoral immune response. Co-administration of PBS-57 with a vaccine may be used in methods to stimulate one or more of a humoral immune response, a CD4+ T cell response, and a CD8+ cytotoxic T cell response.
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