Process for the preparation, of 2-(2-hydroxyphenyl)-benz [1, 3] oxazin-4-one and its use for preparation of 4-[3, 5-bis (2-hydroxyphenyl)-IH-I, 2, 4-triazolTI-yl] benzoic acid
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United States of America Patent
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Dec 9, 2014
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app pub date -
Aug 23, 2011
filing date -
Aug 25, 2010
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Abstract
The invention provides a novel process for the synthesis of 2-(2-hydroxyphenyl)-benz[1,3]oxazin-4-one, the process comprising of reacting the salicylic acid with salicylamide in the presence of p-toluenesulfonyl chloride, base and solvent. The use of 2-(2-hydroxyphenyl)-benz[1,3]oxazin-4-one in the preparation of Deferasirox is also disclosed in the invention.
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- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
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DAVULURI RAMAMOHAN RAO | HYDERABAD 500 034 |
International Classification(s)
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
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Batthni, Guruswamy | Hyderabad, IN | 1 | 0 |
# of filed Patents : 1 Total Citations : 0 | |||
Davuluri, Ramamohan Rao | San Clemente, US | 5 | 9 |
# of filed Patents : 5 Total Citations : 9 | |||
Dummu, Santhosh | Srikakulam, IN | 1 | 0 |
# of filed Patents : 1 Total Citations : 0 | |||
Medida, Chandra Murthy V R | East Godavari, IN | 1 | 0 |
# of filed Patents : 1 Total Citations : 0 | |||
Ponnaiah, Ravi | Madurai, IN | 21 | 15 |
# of filed Patents : 21 Total Citations : 15 |
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