Nucleotide and amino acid sequences relating to respiratory diseases and obesity

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United States of America Patent

PATENT NO 8907067
SERIAL NO

13341457

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Abstract

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This invention relates to genes identified from human chromosome 12q23-qter, which are associated with various diseases, including asthma. The invention also relates to the nucleotide sequences of these genes, isolated nucleic acids comprising these nucleotide sequences, and isolated polypeptides or peptides encoded thereby. The invention further relates to vectors and host cells comprising the disclosed nucleotide sequences, or fragments thereof, as well as antibodies that bind to the encoded polypeptides or peptides. Also related are ligands that modulate the activity of the disclosed genes or gene products. In addition, the invention relates to methods and compositions employing the disclosed nucleic acids, polypeptides or peptides, antibodies, and/or ligands for use in diagnostics and therapeutics for asthma and other diseases.

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Patent Owner(s)

Patent OwnerAddress
OSCIENT PHARMACEUTICALS CORPORATIONWALTHAM MA 02415

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Allen, Kristina Hopkinton, US 22 61
Del, Mastro Richard G Norfolk, US 9 89
Dupuis, Josée Newton, US 4 4
Keith, Tim Bedford, US 37 294
Little, Randall D Newtonville, US 16 115
Pandit, Sunil D Gaithersburg, US 6 4
Simon, Jason Westfield, US 21 105
Van, Eerdewegh Paul Weston, US 21 147

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