Bi-functional shRNA targeting Stathmin 1 and uses thereof
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United States of America Patent
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Dec 9, 2014
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app pub date -
Mar 1, 2012
filing date -
Nov 9, 2006
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Abstract
The present invention includes bifunctional shRNAs capable of reducing an expression of a Stathmin 1 gene; wherein at least one target site sequence of the bifunctional RNA molecule is located within the Stathmin 1 gene, wherein the bifunctional RNA molecule is capable of activating a cleavage-dependent and a cleavage-independent RNA-induced silencing complex for reducing the expression level of Stathmin 1.
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