MicroRNA (miRNA) for the diagnosis and treatment of heart diseases

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United States of America Patent

PATENT NO 8906870
SERIAL NO

12445042

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Abstract

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The invention relates to microRNAs (miRNAs) for the diagnosis, prophylaxis and/or treatment of heart diseases. It relates in particular to SEQ ID No: 1 to SEQ ID No: 29 for the diagnosis, prophylaxis and/or treatment of heart diseases. In addition, the invention relates to the use of these sequences to produce a medicament for heart diseases and for the diagnosis thereof. Also encompassed are a method for the diagnosis of a heart disease, a kit and an expression vector comprising these sequences, a cell which contains the expression vector, and also a method for modulating a heart disease and a method for screening a pharmaceutically active compound for the treatment and/or prophylaxis of a heart disease.

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Patent Owner(s)

Patent OwnerAddress
CARDIOR PHARMACEUTICALS GMBHFEODOR-LYNEN-STR 15 HANNOVER 30625

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bauersachs, Johann Wuerzburg, DE 10 85
Thum, Thomas Wuerzburg, DE 34 116

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