6-amino quinazoline or 3-cyano quinoline derivatives, preparation methods and pharmaceutical uses thereof

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United States of America Patent

PATENT NO 8901140
SERIAL NO

13395892

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Abstract

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6-amino quinazoline or 3-cyano quinoline derivatives, preparation methods and pharmaceutical uses thereof are disclosed. Specifically, the present disclosure discloses novel 6-amino quinazoline or 3-cyano quinoline derivatives presented by general formula (I), or tautomers, enantiomers, diastereomers, racemates or pharmaceutically acceptable salts thereof, or metabolites, metabolic precursors or prodrugs thereof, and their uses as treatment agents especially as protein kinase inhibitors, in which each substitutent group of general formula (I) is as defined in the specification.

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Patent Owner(s)

Patent OwnerAddress
SHANGHAI HENGRUI PHARMACEUTICAL CO LTDNO 279 WENJING ROAD MINHANG DISTRICT SHANGHAI 200245
JIANGSU HENGRUI MEDICINE CO LTD222047 NO 7 KUNLUN MOUNTAIN ROAD LIANYUNGANG ECONOMIC AND TECHNOLOGICAL DEVELOPMENT ZONE JIANGSU LIANYUNGANG CITY JIANGSU PROVINCE 222047

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Lijun Shanghai, CN 50 55
Li, Xin Shanghai, CN 946 7137
Tang, Peng Cho Shanghai, CN 162 3817
Wang, Bin Shanghai, CN 1095 9516
Wang, Jun Shanghai, CN 2215 18848

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