Protein constructs designed for targeting and lysis of cells
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United States of America Patent
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Dec 2, 2014
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app pub date -
Nov 23, 2006
filing date -
Nov 23, 2005
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Abstract
The invention relates to a protein construct, comprising (i) a targeting moiety that is capable of binding to a target cell, and (ii) an effector immunogenic moiety that is capable of triggering an existing, vaccine-induced or natural, immune response. The protein construct, that is preferably in the form of a heteromultimeric protein, is useful for redirecting an immune response that was pre-existing in a patient, toward an undesired target cell.
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