Microfluidic chip devices and their use
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United States of America Patent
Stats
-
Nov 25, 2014
Issued Date -
N/A
app pub date -
Apr 9, 2009
filing date -
Apr 10, 2008
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
A microfluidic chip device (MCD) and its use for performing miniaturized assays on magnetic microbeads (MMs) are described. The MCD is particularly useful for carrying out miniaturized transcript analysis by aiding affinity capturing (TRAC) assays, including PCR. The MCD comprises at least one reaction chamber with sealable liquid connections and at least one fluidic pillar filter in each chamber. The fluidic pillar filter comprises rods with spacings allowing MMs to pass. The sealable liquid connections feed liquid to the reaction chamber, wherein air bubbles are removed. The liquid stream contacts the MMs, which are manipulated with a magnetic rod. The liquid connections enable trapping of the MMs behind the pillar filters or in the channel, while the liquid is changed.
First Claim
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International Classification(s)
Cited Art Landscape
Patent Citation Ranking
- 8 Citation Count
- C12Q Class
- 20.93 % this patent is cited more than
- 11 Age
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | May 25, 2026 |
