Methods and kits useful for the identification of astrocytoma, it's grades and glioblastoma prognosis

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8883419
SERIAL NO

12811976

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The present invention relates to novel primers for identification of astrocytoma, it's grades and glioblastoma prognosis. Further, disclosed is a method of diagnosing the presence of different grades of diffuse astrocytoma and glioblastoma, in a human subject, which involves detection of the expression levels of said genes in tumor tissue samples in comparison to normal brain. Also disclosed is a method of distinguishing between the two types of Glioblastoma—the progressive and de novo types. Also disclosed is a method of prognosis of glioblastoma based on the expression of the gene PBEF1, wherein the higher level of expression of the gene in the tumor sample, indicates poorer survival of the human subject. The disclosed compositions are useful, for example, in the diagnosis, prevention, treatment and/or prognosis of astrocytoma. The invention further provides kits for the detection and prognosis of the said diseases.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCHNEW DELHI

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Balasubramaniam, Anandh Bangalore, IN 1 0
Chandramouli, Ashwathnarayana Rao Bangalore, IN 1 0
Hedge, Alangar Sathyaranjandas Bangalore, IN 1 0
Kondaiah, Paturu Bangalore, IN 5 3
Rao, Manchanahalli Rangaswamy Sathyanarayana Bangalore, IN 1 0
Santosh, Vani Bangalore, IN 3 6
Somasundaram, Kumaravel Bangalore, IN 4 8

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
11.5 Year Payment $7400.00 $3700.00 $1850.00 May 11, 2026
Fee Large entity fee small entity fee micro entity fee
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00