Method for preparing 3-keto-benzofurane derivatives
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United States of America Patent
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Oct 28, 2014
Grant Date -
Jun 27, 2013
app pub date -
Mar 30, 2011
filing date -
Mar 30, 2010
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Abstract
The invention relates to a method for preparing 3-keto-benzofurane derivatives of the general formula: Formula (I), where R is an alkyl or aryl group, R1 is hydrogen or an alkyl or aryl group, and R2 is a substituted alkyl or phenyl group. Said preparation method involves coupling a derivative of Formula III, where X is chlorine, bromine, or iodine or a sulfonate grouping: Formula (III) with a sulfonamide derivative of the formula R—SO2—NH2 in the presence of a basic agent and a catalytic system formed of a complex between a palladium compound and a ligand.
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