Method for inducing tissue growth, differentiation and/or regeneration by delivering a GDF-5 related precursor protein

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United States of America Patent

PATENT NO 8871710
SERIAL NO

13721513

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Abstract

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This invention relates to the production and use of pharmaceutical growth factor compositions with novel characteristics, e.g. improved solubility and controlled release characteristics under physiological conditions. The compositions of one or more precursor proteins of growth factors of the GDF family provoke morphogenic effects such as growth, differentiation, protection and regeneration of a variety of tissues and organs, e.g. bone, cartilage, tendons, ligaments, nerves and skin. The compositions can be advantageously used for the healing of tissue-destructive injuries and for the prevention or therapy of degenerative disorders.

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Patent Owner(s)

Patent OwnerAddress
BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA MBHHEIDELBERG

International Classification(s)

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  • 2012 Application Filing Year
  • A61K Class
  • 11964 Applications Filed
  • 9694 Patents Issued To-Date
  • 81.03 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201220132014201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ploeger, Frank Heidelberg, DE 6 15
Pohl, Jens Hambruecken, DE 138 1858

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Patent Citation Ranking

  • 2 Citation Count
  • A61K Class
  • 21.20 % this patent is cited more than
  • 11 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges1767499999127813872291511752101 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0250500750100012501500175020002250250027503000325035003750400042504500475050005250

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