Methods and devices of separating molecular analytes
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United States of America Patent
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Oct 21, 2014
Grant Date -
Jun 14, 2012
app pub date -
Aug 18, 2010
filing date -
Aug 18, 2009
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Abstract
A method of separating a mixture of a plurality of molecular analytes having different isoelectric points (pIs). The method comprises placing a solution containing a mixture of a plurality of molecular analytes in a separation volume, generating a pH profile having a plurality of pH zones across an axis of the separation volume, and adjusting a profile of the pH profile to induce a migration of a first molecular analyte along the axis apart from a second molecular analyte. The first and second molecular analytes having different pIs.
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