Dual cation dual anion coordination complexes

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United States of America Patent

PATENT NO 8859824
SERIAL NO

12651927

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Abstract

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Compounds are provided herein which are coordination complexes of the formula, AxByCit2Fz.mH2O, wherein A is a cation selected from certain IA or IIA metal ions in the Periodic Table; B is a cation selected from certain IIA metal ions and certain divalent d-block transition metal ions; A and B are different; “Cit” is tribasic citric acid anion; the stoichiometric ratio of x to y is equal or higher than 1.0 but lower than 8.0; m is 0-12; and z is selected such that electroneutrality is preserved. Compounds provided herein are useful to treat dietary deficiencies, osteoporosis, osteopenia, bone loss, and risk of bone loss, as well as other medical conditions involving the need for administration of the various ions. In addition, the compounds can be used as fluoride sources for dental use and to fluoridate water systems.

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Patent Owner(s)

Patent OwnerAddress
MISSION PHARMACAL COMPANY1099 IH-10 WEST SUITE 1000 SAN ANTONIO TX 78278

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gao, Jian Helotes, US 749 2595
Walsdorf, Neill Bailey San Antonio, US 1 0
Walter, Mary Ann La Vernia, US 8 425

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