Process for the preparation of lurasidone hydrochloride
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United States of America Patent
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Oct 7, 2014
Grant Date -
Aug 28, 2014
app pub date -
Feb 20, 2014
filing date -
Feb 22, 2013
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Abstract
Disclosed is a new and efficient process for the synthesis with high yields and purity of lurasidone hydrochloride, a medicament which is useful as a psychotropic substance. The process involves the preparation of lurasidone base in a reaction system not containing inorganic salts, followed by conversion of the latter to an addition salt with an organic carboxylic acid, which is finally converted to lurasidone hydrochloride.
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