Oligopeptide improving differentiation of osteoblasts
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United States of America Patent
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Oct 7, 2014
Grant Date -
Dec 13, 2012
app pub date -
Feb 26, 2010
filing date -
Feb 26, 2010
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Abstract
The present disclosure relates to oligopeptides applicable to a dental implant, which are selected from the group consisting of PEP7 (SEQ ID NO:1), PEP71 (SEQ ID NO:2), EP72 (SEQ ID NO:3), PEP73 (SEQ ID NO:4), PEP74 (SEQ ID NO:5), PEP75 (SEQ ID NO:6) and PEP76 (SEQ ID NO:7). The oligopeptides have very high reactivity for a BMP-specific receptor to increase osteoblastic differentiation and calcification, thereby showing improved osteointegration and osteogenesis.
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