Cardiac muscle regeneration using mesenchymal stem cells

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United States of America Patent

PATENT NO 8852571
SERIAL NO

13369917

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Disclosed is a method for producing cardiomyocytes in vivo by administering to the heart of an individual a cardiomyocyte producing amount of mesenchymal stem cells. These cells can be administered as a liquid injectible or as a preparation of cells in a matrix which is or becomes solid or semi-solid. The cells can be genetically modified to enhance myocardial differentiation and integration. Also disclosed is a method for replacing cells ex vivo in a heart valve for implantation.

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MESOBLAST INTERNATIONAL SÀRLROUTE DE PRE-BOIS 20 MEYRIN 1217

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gordon, Stephen L Columbia, US 26 845
Mackay, Alastair Morgan Timonium, US 16 608
Martin, Bradley J Ellicott City, US 15 365
Pittenger, Mark F Severna Park, US 45 1533

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  • 17 Citation Count
  • A61K Class
  • 81.20 % this patent is cited more than
  • 11 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges1767499999127813872291511752101 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0250500750100012501500175020002250250027503000325035003750400042504500475050005250

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