Inhibitors of protein tyrosine kinase activity

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United States of America Patent

PATENT NO 8846927
APP PUB NO 20130165477A1
SERIAL NO

13767506

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Abstract

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This invention relates to compounds that inhibit protein tyrosine kinase activity. In particular the invention relates to compounds that inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of VEGF receptor signaling and HGF receptor signaling. More particularly, the invention relates to compounds, compositions and methods for the inhibition of VEGF receptor signaling and HGF receptor signaling. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.

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Patent Owner(s)

Patent OwnerAddress
MIRATI THERAPEUTICS INC9393 TOWNE CENTRE DRIVE SUITE 200 SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Claridge, Stephen William Montreal, CA 22 275
Gaudette, Frederic Laval, CA 18 293
Isakovic, Ljubomir Beaconsfield, CA 18 357
Mannion, Michael Montreal, CA 24 362
Raeppel, Stephane St. Lazare, CA 25 499
Saavedra, Oscar Mario Montreal, CA 14 220
Vaisburg, Arkadii Kirkland, CA 56 936
Zhan, Lijie Montreal, CA 21 255

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