-inositol mannosides with an inhibitory activity of the inflammatory response
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United States of America Patent
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Sep 30, 2014
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app pub date -
May 20, 2009
filing date -
May 23, 2008
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Abstract
The present invention relates to novel synthetic analogs of phosphatidyl-myo-inositol mannosides (hereinafter referred to as PIMs) of general formula (I): or a pharmaceutically acceptable salt thereof, to the method for preparing same and to the use thereof in the prevention or treatment of a disease associated with the overexpression of cytokines or of chemokines, in particular of TNF and/or of IL-12. The invention also relates to a pharmaceutical composition comprising at least one synthetic derivative of PIM.
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