C-17 and C-3 modified triterpenoids with HIV maturation inhibitory activity

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United States of America Patent

PATENT NO 8846647
APP PUB NO 20130035318A1
SERIAL NO

13359727

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Abstract

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Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-17 and C-3 modified triterpenoids that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II and III:

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Patent Owner(s)

Patent OwnerAddress
VIIV HEALTHCARE UK (NO 4) LIMITEDSTEVENAGE SG1 2NY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Jie Madison, US 1059 5911
Chen, Yan Guilford, US 884 10448
Liu, Zheng Beacon Falls, US 491 1992
Meanwell, Nicholas A East Hampton, US 189 2698
Regueiro-Ren, Alicia Middletown, US 73 432
Sin, Ny East Hampton, US 42 912
Sit, Sing-Yuen Meriden, US 66 596
Swidorski, Jacob Southington, US 32 149
Venables, Brian Lee Durham, US 25 313

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