Processes for the preparation of phosphatides
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United States of America Patent
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Sep 30, 2014
Grant Date -
Feb 11, 2010
app pub date -
Jul 14, 2009
filing date -
Aug 7, 2008
priority date (Note) -
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Abstract
The present invention discloses processes for the preparation of phosphatides and salts thereof, the processes including the steps of: using at least one raw material lecithin as a substrate and a water-insoluble surfactant-matrix material having a particulate size greater than about 0.01 mm; and enzymatically processing at least one raw material lecithin with the water-insoluble surfactant-matrix material, phospholipase-D, racemic or enantiomerically-pure serine, amino acid, and/or amine and salts in a pH-buffered aqueous solution, wherein the step of processing is performed in a single-phase reaction environment, to produce phosphatides, or the salts thereof, having a structural fatty-acid chain derived from at least one raw material lecithin. Preferably, the step of processing is performed in the presence of a buffer having a pH in the range of about 4.5-8.0. Preferably, the step of processing is performed in the presence of a calcium salt.
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