Method for creating perfusable microvessel systems

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United States of America Patent

PATENT NO 8846307
SERIAL NO

12541707

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Abstract

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Creating a tissue structure in vitro includes juxtaposing mandrels on a culture/perfusion device frame where the mandrels are spaced apart substantially parallel to each other and connecting the mandrels to tubes including an upstream tubes and downstream tubes. The upstream tubes are connected with an upstream manifold and the downstream tubes are connected to a downstream manifold. The frame and the mandrels are sterilized, coated and seeded with cells that multiply and form circular layers around each of the mandrels until the circular layers merge into a tissue structure which is subjected to a growth medium. The mandrels are extracted and the tissue structure is perfused.

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Patent Owner(s)

Patent OwnerAddress
QURIS TECHNOLOGIES LTD114 YIGAL ALON STREET TEL-AVIV 6744320

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Neumann, Thomas Seattle, US 69 715

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