Fibronectin aggrecan biomarker for the identification of spinal and joint source of pain
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United States of America Patent
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Sep 23, 2014
Grant Date -
Mar 28, 2013
app pub date -
Nov 20, 2012
filing date -
Oct 16, 2008
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Abstract
Biomarkers, including isolated fibronectin-aggrecan complexes that correlate with spinal or joint pain and inflammation, and methods for their detection are provided. Also provided are methods for identifying treatment sites in the spine or joint for treatment of pain and inflammation by detecting the presence of, or increased levels of, fibronectin-aggrecan complexes. Methods for treating spinal or joint pain and inflammation are also provided.
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