Asymmetric synthesis of norcantharidin analougus by alkynylation of oxabenzonorbornadienes and their anticancer activities

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United States of America Patent

PATENT NO 8835658
APP PUB NO 20140187801A1
SERIAL NO

13729479

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Abstract

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The present invention relates to a type of norcantharidin analogues and a method to synthesis such norcantharidin analogues by transition metal-catalyzed alkynylation of 7-oxabenzonorbornadienes. The present invention also relates to the use of such norcantharidin analogues in manufacture of a medicament for the treatment of cancer tumors.

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Patent Owner(s)

Patent OwnerAddress
HONG KONG BAPTIST UNIVERSITYKOWLOON TONG KOWLOON
YUNNAN UNIVERSITY OF NATIONALITIES650031 NO 121 134 AVENUE KUNMING YUNNAN KUNMING CITY YUNNAN PROVINCE 650031

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bian, Zhaoxiang Kowloon, HK 41 7
Chan, Albert Sun-Chi Kowloon, HK 25 104
Fan, Baomin Yunnan, CN 5 15
Hu, Jun Yunnan, CN 339 1717
Huang, Chao Yunnan, CN 185 921
Lin, Chengyuan Yunnan, CN 33 16
Lu, Aiping Yunnan, CN 27 7
Wang, Jun Yunnan, CN 2215 18848
Xu, Jianbin Yunnan, CN 15 22
Yang, Qingjing Yunnan, CN 2 0

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