Method for producing dichloropyrazine derivative
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United States of America Patent
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Sep 16, 2014
Grant Date -
Jan 23, 2014
app pub date -
Sep 25, 2013
filing date -
Jan 28, 2009
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Abstract
A method for producing a hydroxypyrazine derivative represented by formula (I) (wherein R1 represents a halogen atom), the method including reacting a pyrazine derivative represented by formula (III) (wherein R2 represents a nitrile group, an N-unsubstituted or N-substituted carbamoyl group, an ester group or a carboxyl group, M represents a cation capable of forming a salt, and n represents a number corresponding with the valence of M) with a halogenating agent. According to the present invention, a hydroxypyrazine derivative that functions as a production intermediate for the dichloropyrazine derivative can be produced efficiently at low cost.
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