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United States of America Patent

PATENT NO 8835619
SERIAL NO

12624288

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Abstract

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The present invention is directed to heat shock proteins from Mycobacterium leprae as well as their encoding polynucleotides and vectors and host cells containing these polynucleotides. These heat shock proteins and their encoding polynucleotides are useful in detection of Mycobacterium leprae. In addition, the heat shock protein can be used as an adjuvant in a pharmaceutical composition containing an antigen to induce or enhance the immune response against the antigen. Further, the heat shock protein may be used to treat atopic conditions or as a vaccine against Mycobacterium leprae. Alternatively, the heat shock protein can be used to form a fusion protein with an antigen to induce or enhance the immune response against the antigen.

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Patent Owner(s)

Patent OwnerAddress
NEW YORK UNIVERSITY70 WASHINGTON SQUARE SOUTH NEW YORK NY 10012

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Levis, William R New York, US 8 141
Martiniuk, Frank T Wood-Ridge, US 3 1

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