Crystalline forms of trans-7-oxo-6-(sulphooxy)-1,6-diazabicyclo[3,2,1]octane-2-carboxamide sodium salt

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United States of America Patent

PATENT NO 8835455
APP PUB NO 20130267480A1
SERIAL NO

13901724

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Abstract

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The present invention relates to novel crystalline forms of sodium salt of trans-7-oxo-6-(sulphooxy)-1,6-diazabicyclo[3,2,1]octane-2-carboxamide (e.g., NXL-104) thereof. The present invention relates to compositions comprising a crystalline form of sodium salt of trans-7-oxo-6-(sulphooxy)-1,6-diazabicyclo[3,2,1]octane-2-carboxamide (e.g., NXL-104) alone or in combination with an antibacterial agent (e.g., ceftaroline fosamil). Processes for the preparation of the crystalline forms and methods of treating bacterial infections by administering the crystalline forms alone or in combination with an antibacterial agent (e.g., ceftaroline fosamil) are also described.

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Patent Owner(s)

  • FOREST LABORATORIES HOLDINGS LIMITED;NOVEXEL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bhattacharya, Sisir Hauppauge, US 6 117
Bonnet, Alain Chateau-Thierry, FR 28 409
Dedhiya, Mahendra G Pomona, US 68 590
Ducandas, Véronique Vitry sur Seine, FR 4 113
Giuliani, Alexandre Villecresnes, FR 15 137
Priour, Alain Paris, FR 8 205
Ravaux, Valérie Reyrieux, FR 4 113
Spargo, Peter Deal, GB 4 68

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