Materials and methods related to sodium/potassium adenosine triphosphase and cholesterol
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United States of America Patent
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Sep 16, 2014
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Nov 15, 2012
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Jan 13, 2011
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Jan 13, 2010
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Abstract
This invention is based in part on the elucidation of new structural conformations and functions of the sodium/potassium adenosine triphosphate synthase (Na/K ATPase), and especially elucidation of new binding sites and interactions. The present invention provides practical applications of several surprising structural and functional relationships between Na/K ATPase and compounds which interact with Na/K ATPase. Disclosure of these structures and relationships provides insight and practical solutions to chemically affecting not only the Na/K ATPase interactions, but also regulators known to be upstream and downstream.
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