Mutant tat proteins and uses thereof
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United States of America Patent
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Sep 9, 2014
Grant Date -
May 10, 2012
app pub date -
Nov 9, 2011
filing date -
Nov 10, 2010
priority date (Note) -
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Abstract
Disclosed are viral proteins associated with Human Immunodeficiency Virus (HIV) infections and mutants thereof, particularly, mutant Tat proteins capable of modulating multiple steps of the HIV-1 replication cycle. Also provided are methods of using the mutant Tat proteins, and pharmaceutical compositions comprising the same, for prevention and treatment of HIV-1 infections, and/or symptoms associated therewith.
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