Use of focused light scattering techniques in biological applicationa
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United States of America Patent
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Sep 9, 2014
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Jul 14, 2009
filing date -
Aug 6, 2008
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Abstract
Methods for using focused light scattering techniques for the optical sensing of biological particles suspended in a liquid medium are disclosed. The optical sensing enables one to characterize particles size and/or distribution in a given sample. This, in turn, allows one to identify the biological particles, determine their relative particle density, detect particle shedding, and identify particle aggregation. The methods are also useful in screening and optimizing drug candidates, evaluating the efficacy and dosage levels of such drugs, and in personalized medicine applications.
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