Modulation of intracellular calcium concentration using non-excitatory electrical signals applied to the tissue
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United States of America Patent
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Sep 2, 2014
Grant Date -
Feb 27, 2003
app pub date -
Apr 3, 2002
filing date -
Jan 8, 1996
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Abstract
According to a method and device for modulating intracellular calcium concentration in biological tissue, a stimulation probe is applied to the tissue, a non-excitatory stimulation pulse is generated, and the pulse is conveyed to the stimulation probe. In one embodiment concerning cardiac tissue, a stimulation probe is applied to a patient's heart, a signal is received from at least one sensor responsive to the patient's cardiac muscle activity, a non-excitatory stimulation pulse responsive to the signal is generated, and the pulse is conveyed to the stimulation probe.
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