Activated collagen scaffold materials and their special fused active restoration factors
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United States of America Patent
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Aug 12, 2014
Grant Date -
Dec 10, 2009
app pub date -
Dec 1, 2006
filing date -
Dec 26, 2005
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Abstract
Provided are activated collagen scaffold materials as well as their special fused active restoration factors useful for promoting tissue repair, such as bone damage repair or nerve injury repair. The special fused active restoration factors are fusion proteins comprising a collagen-binding domain (CBD) at N-/C-terminus of cytokines, wherein the collagen-binding domain is a polypeptide consisting of 7-27 amino acid residues with a conservative sequence shown in SEQ ID NO:1 at N-terminus.
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