Human epidermal growth factor receptor variant lacking an exon

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United States of America Patent

PATENT NO 8796421
APP PUB NO 20130236465A1
SERIAL NO

13879538

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Abstract

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The present invention provides an epidermal growth factor receptor variant-de4 EGFR protein. The variant lacks the fourth exon of the epidermal growth factor receptor, and promotes tumor cell invasion/metastasis. The present invention also provides an encoding gene for the variant and a method of producing the variant by means of recombination technology.

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Patent Owner(s)

Patent OwnerAddress
SHANGHAI CANCER INSTITUTENO 25 LANE 2200 XIETU ROAD XUHUI DISTRICT SHANGHAI 200240 SHANGHAI CITY SHANGHAI CITY 200240

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gu, Jianren Shanghai, CN 12 37
Li, Zonghai Shanghai, CN 43 57
Shi, Bizhi Shanghai, CN 6 30
Wang, Hai Shanghai, CN 243 3208
Wang, Hongyang Shanghai, CN 33 161
Yang, Shengli Shanghai, CN 14 40
Zhou, Min Shanghai, CN 195 1814

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