Oligomer-corticosteroid conjugates
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United States of America Patent
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Aug 5, 2014
Grant Date -
Nov 11, 2010
app pub date -
Oct 3, 2008
filing date -
Oct 5, 2007
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Abstract
The invention provides corticosteroids that are chemically modified by covalent attachment of a water soluble oligomer. A compound of the invention, when administered by any of a number of administration routes, exhibits a reduced biological membrane crossing rate as compared to the biological membrane crossing rate of the corticosteroid not attached to the water soluble oligomer.
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