Biaryl PDE4 inhibitors for treating inflammatory, cardiovascular and CNS disorders

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United States of America Patent

PATENT NO 8791267
APP PUB NO 20120183522A1
SERIAL NO

13430164

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Abstract

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The present invention relates to a genus of biaryl compounds containing at least one further ring. The compounds are PDE4 inhibitors useful for the treatment and prevention of stroke, myocardial infarct and cardiovascular inflammatory diseases and disorders. The compounds have general formula I:

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Patent OwnerAddress
DECODE GENETICS EHF101 REYKJAVIK

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burgin, Alex Kingston, US 30 164
Gurney, Mark E Grand Rapids, US 88 598
Hagen, Timothy Lisle, US 9 11
Hategan, Georgeta Naperville, US 28 132
Kiselyov, Alexander San Diego, US 29 280
Motta, Adalie Naperville, US 3 6
Sandanayaka, Vincent Northboro, US 26 226
Schiltz, Gary Naperville, US 4 6
Singh, Jasbir Naperville, US 100 683

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