Method for the production of sulphonylpyrroles as HDAC inhibitors
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United States of America Patent
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Jul 22, 2014
Grant Date -
May 5, 2011
app pub date -
Mar 11, 2009
filing date -
Mar 12, 2008
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Abstract
Process for the preparation of a compound of formula (I) wherein R1, R2, R3, R4, R5 and R6 have the meanings as defined in the specification, comprising the step of reacting an acrylic acid chloride compound of formula (II′): wherein R1, R2, R3, R4, R5 and R6 have the meanings as defined in the specification, with aqueous hydroxylamine and optionally converting the resulting compound into an acid addition salt thereof.
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