Agents capable of downregulating an MSF-A-dependent HIF-1alpha and use thereof in cancer treatment
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United States of America Patent
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Jul 22, 2014
Grant Date -
May 24, 2012
app pub date -
Feb 6, 2012
filing date -
Jul 12, 2004
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Abstract
Methods and pharmaceutical compositions for the treatment of cancer or acute ischemia are provided. Also provided are methods of identifying agents capable of preventing the formation of or dissociating the MSF-A-HIF-1alpha protein complex, and methods of determining the prognosis of an individual having cancer by identifying the presence or absence of such a protein complex.
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