Selective chemokine modulation

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8784845
APP PUB NO 20100203089A1
SERIAL NO

12441000

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Abstract

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The present invention teaches the use of a metal or an oxide of a metal having a capability of reducing the amount of the chemokine IP-IO in a sample and/or reducing the production of IP-IO in cells. The metal is a metal of group 4 or 5 in the periodic table of the elements and preferably titanium. These metals and metal oxides can selectively bind IP-IO to its surface to thereby scavenge IP-IO from the surrounding medium. In addition, a metal-cell contact induces a reduction in the production of IP-IO from IP-IO producing cells. The metals and metal oxides of the present invention can therefore be used for treating and/or preventing medical conditions characterized by adverse IP-IO expression, such as inflammatory reactions.

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Patent Owner(s)

Patent OwnerAddress
PROPHY MED AB260 40 VIKEN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bruce, Lars Viken, SE 29 132
Lyngstadaas, Staale Petter Nesoddtangen, NO 12 187

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