Camptothecin derivatives as chemoradiosensitizing agents

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United States of America Patent

PATENT NO 8779138
APP PUB NO 20110184009A1
SERIAL NO

13012772

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Abstract

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Camptothecin-based compounds are useful for treating a neoplasm in mammalian subjects by administering such compound to the subjects in combination with radiotherapy, i.e., the treatment of tumors with radioactive substances or radiation from a source external to the subject. Camptothecin-based compounds are modified by positioning at least one electron-affinic group around the camptothecin structure to enhance their value in combination with radiotherapy. New Camptothecin-based compounds are disclosed that are useful for treating cancer by administering the novel compounds alone or in combination with radiotherapy.

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Patent Owner(s)

Patent OwnerAddress
SUTTER WEST BAY HOSPITALS DBA CALIFORNIA PACIFIC MEDICAL CENTER475 BRANNAN STREET SUITE 220 SAN FRANCISCO CA 94107

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Yang, Li-Xi San Francisco, US 24 138

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