Insertable medical devices with a porous bed for delivering nano-carriers to a target site and methods of preparing the same
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United States of America Patent
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Jul 15, 2014
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app pub date -
Jan 19, 2011
filing date -
Jan 22, 2010
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Abstract
The invention discloses a method of coating a medical device. The method includes applying a coating composition on the medical device to form a layer on the medical device. The coating composition includes one or more of one or more biological agents and heparin dissolved in a mixture of a first solvent and a second solvent. The first solvent and the second solvent have different evaporation temperatures. Subsequently, at least a part of one of the first solvent and the second solvent present in the coating composition is evaporated to create a plurality of pores in the layer. Thereafter, one or more drugs are deposited in the plurality of pores. When the medical device is positioned and expanded at a target site, the one or more drugs are released from the plurality of pores.
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