Streptospirole derivatives
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United States of America Patent
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Jul 1, 2014
Grant Date -
Dec 1, 2011
app pub date -
Jul 16, 2009
filing date -
Jul 31, 2008
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Abstract
The invention relates to streptospirole derivatives of the general formula (I), wherein R1, R2, R3, X1, X2, Y1 and Y2 are as defined herein, a process for the preparation of said compounds by fermenting the microorganism Streptomyces sp. ST 108140 (DSM 19369) and optionally derivatizing the compounds produced by said microorganism, a pharmaceutical composition comprising at least one compound of the formula (I), and the use of a compound of the formula (I) for the preparation of a medicament for the treatment and/or prophylaxis of bacterial infections.
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