Phosphoramidate derivatives of guanosine nucleoside compounds for treatment of viral infections
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United States of America Patent
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Jun 24, 2014
Grant Date -
Mar 1, 2012
app pub date -
Jan 11, 2010
filing date -
Jan 9, 2009
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Abstract
Phosphoramidate compounds derived from guanine bases having enhanced therapeutic potency are provided, and these compounds in particular have enhanced potency with respect to treatment of viral infections, such as hepatitis C virus. Pharmaceutical compositions, methods of preparing the compounds, and methods of using the compounds and compositions to treat viral infections are also provided.
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